Clinicopathologic Features of Retinoblastoma After Primary Chemoreduction
نویسندگان
چکیده
منابع مشابه
Clinicopathologic features of retinoblastoma after primary chemoreduction.
BACKGROUND Primary chemotherapy is a new treatment approach in retinoblastoma, aiming to avoid radiogenic adverse effects, such as second tumor-associated mortality, as observed following external beam irradiation. OBJECTIVE To describe the clinical and histopathologic regression pattern after primary chemotherapy in retinoblastoma. METHODS Five patients with sporadic bilateral retinoblasto...
متن کاملChemoreduction for unilateral retinoblastoma.
OBJECTIVE To evaluate conservative management of unilateral retinoblastoma using chemoreduction and focal treatment. DESIGN Prospective nonrandomized single-center clinical trial. SETTING Ocular Oncology Service at Wills Eye Hospital of Thomas Jefferson University, Philadelphia, Pa, in conjunction with the Division of Oncology at The Children's Hospital of Philadelphia. PARTICIPANTS Thirt...
متن کاملChemoreduction for retinoblastoma may prevent intracranial neuroblastic malignancy (trilateral retinoblastoma).
OBJECTIVE To evaluate whether neoadjuvant intravenous chemotherapy (chemoreduction) for retinoblastoma reduces the risk for associated intracranial neuroblastic tumor (trilateral retinoblastoma). DESIGN Retrospective consecutive case series. PARTICIPANTS Two hundred fourteen consecutive children with newly diagnosed retinoblastoma treated at a major ocular oncology center from January 1, 19...
متن کاملHistopathologic findings in eyes with retinoblastoma treated only with chemoreduction.
OBJECTIVE To evaluate the histopathologic findings in the eyes with retinoblastoma that had been treated only with chemoreduction. DESIGN Clinicopathologic series. Study Material Ten eyes of 8 patients with retinoblastoma that were enucleated after therapy consisting only of systemic chemotherapy (chemoreduction). METHODS All cases received a chemoreduction regimen including a combination o...
متن کاملResolution of iris neovascularization following chemoreduction of advanced retinoblastoma.
Iris neovascularization (NVI) in eyes with newly diagnosed retinoblastoma is a hallmark of advanced tumor. These eyes often display secondary glaucoma and additional partial or complete retinal detachment. From a clinical perspective, NVI with secondary glaucoma is noted in approximately 12% of eyes with retinoblastoma, and from a pathology perspective, NVI has been found in 44% of eyes followi...
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ژورنال
عنوان ژورنال: Archives of Ophthalmology
سال: 1998
ISSN: 0003-9950
DOI: 10.1001/archopht.116.7.887